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Figure 2 | Malaria Journal

Figure 2

From: Immunization with different Pf AMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits

Figure 2

Protein sequence (aa 25 - 545) alignments for DiCo antigens and parasite AMA1 alleles. The recombinant AMA1 allelic antigens for FVO, HB3, 3D7 and CAMP used in ELISA differ at 6 positions (5 for HB3 AMA1) from the respective parasite sequences presented here. These differences (N162Q, T288V, S373 D, N422 D, S423K, N499Q) were introduced in the recombinant antigens to prevent N-glycosylation of the Pichia pastoris-expressed antigens.

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Malaria Journal

ISSN: 1475-2875

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