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Figure 4 | Malaria Journal

Figure 4

From: Immunization with different Pf AMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits

Figure 4

ELISA antibody titre correlates with in vitro parasite growth inhibition. Association of antibody levels with in vitro antibody functionality is shown for parasite strains FCR3 (FVO), HB3 and NF54 (3D7). In vitro inhibition of any parasite strain at 6 mg/ml of purified antibody has been plotted against antibody titres measured with the corresponding AMA1 allele. Plots are based on a four-parameter logistic function. Filled circles represent animals in group 1 (f3h, n = 5), filled triangles represent group 2 (hf3, n = 6), filled squares represent group 3 (h3f, n = 4), open circles represent group 4 (Na mix, n = 6) and open triangles represent group 5 (DiCo mix, n = 6).

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Malaria Journal

ISSN: 1475-2875

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