Table 3 Frequencies of the analyzed single-nucleotide polymorphism (SNPs), before treatment (D₀) and in recurrent infections after treatment with artemether-lumefantrine (R₀)

D₀

All patients

(115+56)/234

73.1 (67.4-78.8)^a

(152+41)/232

83.2 (78.3-88.0)

Patients with recrudescence during follow-up

(5+8)/13

100.0 (100.0-100.0)

(7+5)/13

92.3 (75.6-100.0)

Patients with reinfection during follow-up

(53+33)/115

74.8 (66.7-82.8)^b

(71+23)/113

83.2 (76.2-90.2)

R₀

All patients

(99+30)/138

93.5 (89.3-97.7)^a

(92+15)/126

84.9 (78.6-91.3)

Patients with recrudescence

(12+2)/14

100.0 (100.0-100.0)

(9+2)/13

84.6 (61.9-100.0)

Patients with new infection

(79+25)/112

92.9 (88.0-97.7)^b

(74+13)/104

83.7 (76.4-90.9)