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Table 1 Protection against challenge

From: Daily Plasmodium yoelii infective mosquito bites do not generate protection or suppress previous immunity against the liver stage

Mice experimental conditions

Threshold cycle (Ct) in real time-PCR

Number of mice (protected/total)

Irradiated mosquito bites

> 40

(3/3)

Normal mosquito bites

17 ± 0.85

(0/3)

Immunized

> 40

(3/3)

Immunized + normal mosquito bites

> 40

(3/3)

  1. Groups of mice were challenged with 104 P. yoelii-GFP sporozoites injected intravenously. Real-time PCR was run for 40 cycles, therefore Ct > 40 indicates no detection of parasite in the liver.
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Malaria Journal

ISSN: 1475-2875

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