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Table 1 Clinical and laboratory features of children dying from cerebral malaria due to mixed Plasmodium falciparum/Plasmodium viva x infections

From: A histopathologic study of fatal paediatric cerebral malaria caused by mixed Plasmodium falciparum/Plasmodium vivax infections

 

Patient 1

Patient 2

Patient 3

Age (months)

63

36

94

Sex

Female

Female

Male

Blantyre coma score on admission

0

2

1

Blood lactate (mmol/L)

1.6

6.4

1.0

Plasma bicarbonate (mmol/L)

18

10.2

22.3

Blood glucose (mmol/L)

18.4

3.2

7.0

Haemoglobin (g/L)

69

39

111

Peripheral parasitaemia (/μL) by light microscopy:

   

P. falciparum

154,000

104,000

0

P. vivax

0

80

0

Plasmodium species by nPCR (blood)

Mixed species

Mixed species

Mixed species

Peripheral parasitaemia by qPCR (number of cycles):

   

P. falciparum

26.3

23.1

37.2

P. vivax

41.0

29.2

35.8

Plasmodium species by nPCR (brain)

P. falciparum

P. falciparum

Negative

  1. nPCR, nested polymerase chain reaction [10]; qPCR, quantitative polymerase chain reaction [11]