Table 1 Clinical and epidemiological characteristics and outcomes of 19 cases of imported malaria in pregnancy

Country of Origin

Equatorial Guinea

11

(57.9)

Nigeria

6

(31.6)

Congo

1

(5.3)

Ghana

1

(5.3)

Mean Age Years (+/- SD)

27

(+/-5.3)

Reason for Travel

VFR

17

(89.5)

National Traveller

0

Recent Immigration

Yes

2

(10.5)

Chemoprophylaxis

None/Incorrect/Incomplete

19

(100)

Co-morbidities

None

11

(57.9)

HIV

3

(15.8)

Hypertension

1

(5.3)

Smoker

1

(5.3)

Other

3

(15.8)

Gestational Age

Third Trimester

10

(52.6)

Second Trimester

3

(15.8)

First Trimester

6

(31.6)

Parity

Multigravidae

18

(94.7)

Primigravidae

1

(5.3)

Classification As High Risk Pregnancy

Yes

6

(31.6)

Clinical Presentation

-Asymptomatic

3

(15.8)

-Symptomatic

16

(84.2)

   Fever

14

(73.6)

Fever Alone

7

(36.8)

Fever + Gastrointestinal

4

(21.1)

Fever + Flu-Like Symptoms

3

(15.8)

   Other

2

(10.5)

- Signs

None

17

(89.5)

Splenomegaly (At examination and/or ultrasound)

1

(5.3)

Hepatosplenomegaly (At examination and/or ultrasound)

1

(5.3)

Laboratory Findings

-Anaemia (Hb < 11 g/Dl)

15

(78.9)

   Mild (9-10.9 g/Dl)

6

(31.6)

   Moderate (7-8.9 G/Dl)

6

(31.6)

   Severe (Hb < 7 g/Dl)

3

(15.8)

-Thrombocytopaenia (< 150,000/Mm³)

14

(73.7)

   Mild (100,000-150,000/Mm³)

8

(42.1)

   Moderate (80,000-10,000/Mm³)

2

(10.5)

   Severe (< 80,000/Mm³)

4

(21.1)

-Hypoglycaemia (Serum Glucose < 60 Mg/Dl, With Or Without Symptoms)

2

(10.5)

Microbiology

- P. falciparum (One Mixed Infection)

19

(100)

Parasitaemia > 4%

1

(5.3)

Parasitaemia 1-4%

5

(26.3)

Parasitaemia < 1%

11

(57.9)

No data

2

(26.3)

Diagnostic delay days Median (IR)

7.5

(2.7-21.7)

Treatment

Quinine + Clindamycin

16

(84.2)

Mefloquine

1

(5.3)

Atovaquone + Proguanil*

2

(10.5)

Maternal outcome

- Death

0

(0)

-Clinical complications

0

(0)

-Anaemia improvement (N = 15)

Yes

9

(60)

No data

6

(40)

Foetal outcome

-Abortion

2

(10.5)

-Delivery Term

15

(78.9)

No data (Lost to follow-up)

2

(10.5)

-Birth weight N = 15

> 2,500 g

15

(100)

< 2,500 g

0

(0)

Parasitological follow-up

Undetectable parasitaemia

12

(63.2)

No data

7

(38.9)