Table 1 Factors associated with the presence of the resa2 T1526C allele in P. falciparum infected Beninese patients. Analysis with mixed isolates
From: Possible association of the Plasmodium falciparum T1526C resa2 gene mutation with severe malaria
T1526C SNP | Wild allele | p value | |
|---|---|---|---|
Infected patients n (%) | 16 (16) | 85 (84) | |
Variables | |||
Sex | |||
Male | 8 (50) | 53 (62) | 0.3 |
Female | 8 (50) | 32 (38) | |
Age (months) | |||
Median (min-max) | 39 (7–120) | 48 (4–114) | |
In quartile | |||
<=24 months | 6 (38) | 24 (28) | |
24.1-48 | 4 (25) | 22 (26) | 0.9 |
48.1-84 | 3 (19) | 17 (20) | |
>84 | 3 (19) | 22 (26) | |
Malaria | |||
Severe | 11 (69) | 43 (51) | 0.2 |
Uncomplicated | 5 (31) | 42 (49) | |
Parasitaemia (%) | |||
Median (min-max) | 7 (0.2-36) | 3 (0.01-65) | 0.2 |
By category | |||
>4% | 10 (63) | 32 (38) | 0.06 |
<=4% | 6 (37) | 53 (62) | |
Malaria prophylaxis | |||
Yes | 5 (42) | 30 (41) | 0.9 |
No | 7 (58) | 44 (59) | |
Splenomegalia | |||
Yes | 5 (31) | 27 (32) | 0.9 |
No | 11 (69) | 58 (78) |