Table 3 Malariometric indices by haemoglobin genotype
Infection characteristic | AA (N = 305) | AC (N = 64) | AS (N = 35) | CC (N = 9) | SC (N = 5) | SS (N = 1) | All (N = 419) |
|---|---|---|---|---|---|---|---|
Symptomatic malaria (fever and > 0 parasites/μl), N (%) | 37 (12.1%) | 13 (20.3%) | 2 (5.7%) | 0 (0.0%) | 2 (40.0%) | 0 (0.0%) | 54 (12.9%) |
P. falciparum infection (> 0 parasites/μl), N (%) | 152 (49.8%) | 34 (53.1%) | 19 (54.3%) | 1 (11.1%)* | 4 (80.0%) | 1 (100.0%) | 211 (50.4%) |
Symptomatic malaria (fever and >2500 parasites/μl) | 27 (8.9%) | 9 (14.1%) | 1 (20.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 37 (8.8%) |
P. falciparum infection (> 2500 parasites/μl), N (%) | 84 (27.5%) | 22 (34.4%) | 4 (11.4%)* | 0 (0.0%) | 2 (40.0%) | 1 (100.0%) | 113 (27.0%) |
Gametocyte carriage, N (%) | 60 (19.7%) | 11 (17.2%) | 3 (8.6%) | 2 (22.2%) | 0 (0.0%) | 0 (0.0%) | 76 (18.1%) |
Splenomegaly, N (%) | 26 (8.5%) | 7 (10.9%) | 2 (5.7%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 35 (8.4%) |
Haemoglobin (g/dl), mean (SD) | 10.2 (1.5) | 9.9 (1.4) | 9.9 (1.5) | 10.0 (1.5) | 11.1 (1.1) | 10.5 | 10.1 (1.5) |
P. falciparum density (per/μl), GM (95% CI) | 2690 (1978, 3659) | 5823 (3117, 10878) * | 986 (383, 2541)* | 364 | 1632 (7, 375567) | 9740 | 2748 (2104, 3589) |
Gametocyte density (per/μl), GM (95% CI) | 41 (31, 53) | 20 (11, 37)* | 23 (3, 173) | 34 (4, 263) | (NA) | (NA) | 36 (28, 45) |