|
Season
|
Haemoglobin genotype
|
Number of children
|
Number of episodes
|
Mean number of episodes per child
|
Total person- years
|
Incidence rate (95% CI) (per person-year)
|
|---|
|
Low
|
AA
|
331
|
184
|
0.6
|
177.0
|
1.0 (0.9, 1.2)
|
| |
AC
|
68
|
31
|
0.5
|
37.1
|
0.8 (0.6, 1.2)
|
| |
AS
|
37
|
15
|
0.4
|
20.4
|
0.7 (0.4, 1.2)
|
| |
CC
|
10
|
1
|
0.1
|
5.8
|
0.2 (0.0, 1.0)
|
| |
SC
|
5
|
1
|
0.2
|
2.8
|
0.4 (0.0, 2.0)
|
| |
SS
|
1
|
0
|
0.0
|
0.6
|
0.0 (0.0, 6.4)
|
| |
Total
|
452
|
232
|
0.5
|
243.6
|
1.0 (0.8, 1.1)
|
|
High
|
AA
|
305
|
363
|
1.1
|
112.4
|
3.2 (2.9, 3.6)
|
| |
AC
|
64
|
74
|
1.1
|
23.0
|
3.2 (2.5, 4.0)
|
| |
AS
|
35
|
35
|
0.9
|
13.1
|
2.7 (1.9, 3.7)
|
| |
CC
|
9
|
8
|
0.8
|
3.7
|
2.2 (0.9, 4.3)
|
| |
SC
|
5
|
5
|
1.0
|
1.8
|
2.9 (0.9, 6.7)
|
| |
SS
|
1
|
0
|
0.0
|
0.4
|
0.0 (0.0, 8.8)
|
| |
Total
|
419
|
485
|
1.1
|
154.4
|
3.1 (2.9, 3.4)
|
|
Low and High
|
AA
|
331
|
542
|
1.6
|
288.0
|
1.9 (1.7, 2.0)
|
| |
AC
|
68
|
104
|
1.5
|
59.8
|
1.7 (1.4, 2.1)
|
| |
AS
|
37
|
50
|
1.4
|
33.1
|
1.5 (1.1, 2.0)
|
| |
CC
|
10
|
9
|
0.9
|
9.3
|
1.0 (0.4, 1.8)
|
| |
SC
|
5
|
6
|
1.2
|
4.5
|
1.3 (0.5, 2.9)
|
| |
SS
|
1
|
0
|
0.0
|
1.0
|
0.0 (0.0, 3.7)
|
| |
Total
|
452
|
711
|
1.6
|
395.7
|
1.8 (1.7, 1.9)
|
- Note: Incidence of malaria episodes was calculated as the number of malaria cases.
- divided by total person-years (p-yrs) at risk).
