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Table 4 Incidence of malaria episodes (fever and parasitemia >2500/μl) by haemoglobin genotype and season

From: Haemoglobin variants and Plasmodium falciparum malaria in children under five years of age living in a high and seasonal malaria transmission area of Burkina Faso

Season Haemoglobin genotype Number of children Number of episodes Mean number of episodes per child Total person- years Incidence rate (95% CI) (per person-year)
Low AA 331 184 0.6 177.0 1.0 (0.9, 1.2)
  AC 68 31 0.5 37.1 0.8 (0.6, 1.2)
  AS 37 15 0.4 20.4 0.7 (0.4, 1.2)
  CC 10 1 0.1 5.8 0.2 (0.0, 1.0)
  SC 5 1 0.2 2.8 0.4 (0.0, 2.0)
  SS 1 0 0.0 0.6 0.0 (0.0, 6.4)
  Total 452 232 0.5 243.6 1.0 (0.8, 1.1)
High AA 305 363 1.1 112.4 3.2 (2.9, 3.6)
  AC 64 74 1.1 23.0 3.2 (2.5, 4.0)
  AS 35 35 0.9 13.1 2.7 (1.9, 3.7)
  CC 9 8 0.8 3.7 2.2 (0.9, 4.3)
  SC 5 5 1.0 1.8 2.9 (0.9, 6.7)
  SS 1 0 0.0 0.4 0.0 (0.0, 8.8)
  Total 419 485 1.1 154.4 3.1 (2.9, 3.4)
Low and High AA 331 542 1.6 288.0 1.9 (1.7, 2.0)
  AC 68 104 1.5 59.8 1.7 (1.4, 2.1)
  AS 37 50 1.4 33.1 1.5 (1.1, 2.0)
  CC 10 9 0.9 9.3 1.0 (0.4, 1.8)
  SC 5 6 1.2 4.5 1.3 (0.5, 2.9)
  SS 1 0 0.0 1.0 0.0 (0.0, 3.7)
  Total 452 711 1.6 395.7 1.8 (1.7, 1.9)
  1. Note: Incidence of malaria episodes was calculated as the number of malaria cases.
  2. divided by total person-years (p-yrs) at risk).