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Table 4 Incidence of malaria episodes (fever and parasitemia >2500/μl) by haemoglobin genotype and season

From: Haemoglobin variants and Plasmodium falciparum malaria in children under five years of age living in a high and seasonal malaria transmission area of Burkina Faso

Season

Haemoglobin genotype

Number of children

Number of episodes

Mean number of episodes per child

Total person- years

Incidence rate (95% CI) (per person-year)

Low

AA

331

184

0.6

177.0

1.0 (0.9, 1.2)

 

AC

68

31

0.5

37.1

0.8 (0.6, 1.2)

 

AS

37

15

0.4

20.4

0.7 (0.4, 1.2)

 

CC

10

1

0.1

5.8

0.2 (0.0, 1.0)

 

SC

5

1

0.2

2.8

0.4 (0.0, 2.0)

 

SS

1

0

0.0

0.6

0.0 (0.0, 6.4)

 

Total

452

232

0.5

243.6

1.0 (0.8, 1.1)

High

AA

305

363

1.1

112.4

3.2 (2.9, 3.6)

 

AC

64

74

1.1

23.0

3.2 (2.5, 4.0)

 

AS

35

35

0.9

13.1

2.7 (1.9, 3.7)

 

CC

9

8

0.8

3.7

2.2 (0.9, 4.3)

 

SC

5

5

1.0

1.8

2.9 (0.9, 6.7)

 

SS

1

0

0.0

0.4

0.0 (0.0, 8.8)

 

Total

419

485

1.1

154.4

3.1 (2.9, 3.4)

Low and High

AA

331

542

1.6

288.0

1.9 (1.7, 2.0)

 

AC

68

104

1.5

59.8

1.7 (1.4, 2.1)

 

AS

37

50

1.4

33.1

1.5 (1.1, 2.0)

 

CC

10

9

0.9

9.3

1.0 (0.4, 1.8)

 

SC

5

6

1.2

4.5

1.3 (0.5, 2.9)

 

SS

1

0

0.0

1.0

0.0 (0.0, 3.7)

 

Total

452

711

1.6

395.7

1.8 (1.7, 1.9)

  1. Note: Incidence of malaria episodes was calculated as the number of malaria cases.
  2. divided by total person-years (p-yrs) at risk).