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Table 5 Incidence of malaria episodes (fever and parasitemia >2500 parasites/μl) by haemoglobin genotype and age at enrollment

From: Haemoglobin variants and Plasmodium falciparum malaria in children under five years of age living in a high and seasonal malaria transmission area of Burkina Faso

Age Haemoglobin genotype Number of children Number of episodes Incidence rate (95% CI) (per person-year) District-adjusted rate ratio (95% CI) P value
0-1 yrs AA 52 115 2.7 (2.2, 3.2) --- ---
  AC 15 31 2.5 (1.7, 3.5) 0.93 (0.62, 1.38) 0.72
  AS 2 2 1.1 (0.1, 3.9) 0.41 (0.10, 1.65) 0.21
1-2 yrs AA 66 131 2.3 (2.0, 2.8) --- ---
  AC 16 22 1.5 (1.0, 2.3) 0.66 (0.42, 1.04) 0.07
  AS 9 19 2.5 (1.5, 3.9) 0.93 (0.56, 1.54) 0.77
2-3 yrs AA 70 145 2.5 (2.1, 2.9) --- ---
  AC 10 8 0.9 (0.4, 1.7) 0.37 (0.18, 0.75) 0.01
  AS 14 20 1.6 (1.0, 2.5) 0.63 (0.40, 1.01) 0.06
3-4 yrs AA 77 95 1.4 (1.1, 1.7) --- ---
  AC 17 32 2.2 (1.5, 3.1) 1.61 (1.08, 2.41) 0.02
  AS 6 9 1.7 (0.8, 3.2) 1.05 (0.53, 2.09) 0.89
4-5 yrs AA 66 56 0.9 (0.7, 1.2) --- ---
  AC 10 11 1.2 (0.6, 2.2) 1.27 (0.66, 2.44) 0.48
  AS 6 0 0.0 (0.0, 0.6) 0.00 1.00