Figure 3

The distribution of mean parasitaemia for carriers of the TLR9 SNP genotypes 3a): The mean parasite load for the rs352139 (G + 1174A) GG, GA and AA genotypes are 19,376; 6,268; 5,589 parasite/μl of blood. The *GG genotype was significantly associated with higher parasitaemia compared with the non-GG genotype (19,376 vs. 6,086 parasite/μl of blood, p = 0.01). 3b): The mean parasite load for the rs5743836 (C-1237 T) CC, CT and TT genotypes are 23,532; 14,924; 5,501 parasite/μl of blood, respectively. The *TT genotype was significantly associated with lower parasitaemia compared with the non-TT genotype (5,501 vs. 16,973 parasite/μl of blood, p = 0.03). 3c): The mean parasite load for the rs187084 (C-1486 T) CC, CT and TT genotypes are 20,691; 10,089; 11,117 parasite/μl of blood, respectively. 3d). The mean parasite load for the rs352140 (G + 2848A) GG, GA and AA genotypes are 10,738; 13776; 12088 parasite/μl of blood. Statistical analysis was performed using ANOVA and student’s t-test. P value of <0.05 was considered to be statistically significant.