Table 2 The clinical score of the mice was performed according to the table below
Score | Observation |
|---|---|
0 | No discernible clinical signs |
1 | Hunched back, slightly ruffled fur |
2 | Very ruffled fur, reduced rate of movement, developing motor impairments |
3 | Very ruffled fur, impaired balance/coordination, hypothermic, severe motor impairments such as ataxia, hemiplegia and paraplegia, convulsions, fitting |
4 | Very little movement, convulsions, fitting |
5 | Loss of consciousness/coma |