| |
PCR-corrected
|
Uncorrected
|
|---|
|
DP
|
A+M
|
DP
|
A+M
|
|---|
|
N (%)
|
N (%)
|
N (%)
|
N (%)
|
|---|
|
95% CI
|
95% CI
|
95% CI
|
95% CI
|
|---|
|
ITT Population
|
|
Heterogeneity test
|
p=0.398a
|
p=0.800a
|
|
Guwahati
|
44 (95.7)
|
22 (100)
|
44 (95.7)
|
22 (100)
|
|
(DP=46, A+M=22)
|
89.76; 100
|
n.a.
|
89.76; 100
|
n.a.
|
|
Goa
|
19 (100)
|
8 (88.9)
|
19 (100)
|
7 (77.8)
|
|
(DP=19, A+M=9)
|
n.a.
|
68.4; 100
|
n.a.
|
50.6; 100
|
|
Mangalore
|
18 (50.0)
|
11 (61.1)
|
12 (33.3)
|
5 (27.8)
|
|
(DP=36, A+M=18)
|
33.7; 66.3
|
38.6; 83.6
|
17.9; 48.7
|
7.1; 48.5
|
|
Total
|
81 (80.2)
|
41 (83.7)
|
75 (74.3)
|
34 (69.4)
|
|
(DP=101, A+M=49)
|
72.4; 88.0
|
73.3; 94.0
|
65.7; 82.8
|
56.5; 82.3
|
|
95% CI for DP - A+M
|
−16.4; 9.5
|
−10.6; 20.3
|
|
PP population
|
|
Heterogeneity test
|
p=0.978b
|
p=0.574a
|
|
Guwahati
|
42 (100)
|
22 (100)
|
42 (100)
|
22 (100)
|
|
(DP=42, A+M=22)
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
|
Goa
|
19 (100)
|
8 (100)
|
19 (100)
|
7 (87.5)
|
|
(DP=19, A+M=8)
|
n.a.
|
n.a.
|
n.a.
|
64.6; 100
|
|
Mangalore
|
18 (94.7)
|
11 (100)
|
12 (63.2)
|
5 (45.5)
|
|
(DP=19, A+M=11)
|
84.7; 100
|
n.a.
|
41.5; 84.9
|
16.0; 74.9
|
|
Total
|
79 (98.8)
|
41 (100)
|
73 (91.3)
|
34 (82.9)
|
|
(DP=80, A+M=41)
|
96.3; 100
|
n.a.
|
85.1; 97.4
|
71.4; 94.4
|
|
95% CI for DP - A+M
|
−3.7; 1.2
|
−4.8; 21.4
|
- DP, dihydroartemisinin-piperaquine; A+M, artesunate-mefloquine; n.a., not assessable.
- aBreslow-Day; bLogistic Regression.
