| |
DHA-PQP n/N (%)
|
AS + MQ n/N (%)
|
P-value2
|
|---|
|
Fever prevalence
1
|
|
Day 0
|
99/101 (98.0)
|
49/49 (100.0)
|
1.000
|
|
Day 1
|
45/101 (44.6)
|
21/49 (42.9)
|
0.844
|
|
Day 2
|
30/100 (30.0)
|
14/49 (28.6)
|
0.857
|
|
Day 3
|
23/100 (23.0)
|
10/49 (20.4)
|
0.720
|
|
Day 7
|
13/98 (13.3)
|
7/46 (15.2)
|
0.752
|
|
Overall (day 0 - day 7)
|
99/101 (98.0)
|
49/49 (100.0)
|
1.000
|
|
Person-fever-days3
|
260/695 (374.1)
|
125/334 (374.3)
|
0.994
|
|
Parasitaemia
|
|
Day 0
|
101/101 (100)
|
49/49 (100)
| |
|
Day 1
|
37/101 (36.6)
|
15/49 (30.6)
| |
|
Day 2
|
7/101 (6.9)
|
4/49 (8.2)
| |
|
Day 3
|
0
|
0
| |
- DP = dihydroartemisinin-piperaquine; A + M = artesunate-mefloquine.
- 1Calculated, at a given time (i.e. Day 0, Day 1 etc.), as number of patients with fever (≥37.5°C) divided by the number of patients having reached that time;
- 2Pearson Chi-square or Fisher’s exact test, as appropriate;
- 3Calculated as number of days in which temperature was greater or equal to 37.5 during the first study week divided by the total number of follow up days in the first week and expressed per 1,000 person-days.
