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Table 1 Clinical and biological parameters of Patients characteristics

From: Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

  SMA CM UM P value P value
SMA vs. CM (1) SMA vs. CM vs. UM (2)
No. children 108 144 80   
Age (years) 3.5 (1–5) 3.1 (1–6) 3.8 (2–6) NSb NSb
Sex [n (%)]      
  Male 59 (54.6) 78 (54.2) 44 (55) NSa NSa
  Female 49 (45.4) 66 (45.8) 36 (45) NSa NSa
Hb (g/dL) 4.3 (3.7-4.7) 6.3 (5–8.02) 9.6 (8.4-10.9) = .0001 ≤ .0001
RBC (109/μL) 1.77 (1.5-2) 2.73 (2.2-3.3) 3.9 (3.6-4.2) = .0001 ≤ .078
WBC (106/μL) 12.1 (8.5-19.1) 11.4 (8.3-15.5) 12.4 (8–15.6) NSb NSb
Lymphocyte(106/μL) 5.3 (2.9-8.1) 3 (1.8-4.8) 1.9 (1.5-3.3) NSb ≤ .0051
Monocytes (106/μL) 0.6 (0.3-1.2) 0.5 (0.2-0.9) 0.7 (0.5-0.9) NSb NSb
Parasitaemia 41322(5060–989003) 52356(5676–1872368) 61000(7396–434024) NSb NSb
HCM (%) 3.3 (0–10) 10 (0–20) 0 (0–3.3) = .032 ≤ .039
  1. Values given are medians numbers (25th-75th percentiles) except when indicated otherwise and for parasitaemia [geometric mean (range)]. CM, SMA, UM and AC refer to cerebral malaria, severe malarial anaemia, uncomplicated malaria and asymptomatic controls, respectively. HCM = haemozoin-containing monocytes.
  2. (1) Comparison between SMA and CM.
  3. (2) Comparison between the three groups SMA, CM and UM.
  4. a Statistical significance was obtained using the chi-square test.
  5. b Statistical significance was obtained using the using Mann-Whitney’s test (1) or Kruskal-Wallis’ test (2).