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Table 2 Spontaneous and stimulated IL-10 and TNF production in malaria patients

From: Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

 

Spontaneous

LPS-stimulated

PHA-stimulated

IL-10

SMA

24.3 (11–39.6)

188.8 (70–342)

55.3 (30.8-176.6)

 

CM

201.5 (39–744.8)

623.4 (521.1-1028.25)

608.9 (148.05-725.25)

 

UM

100 (22.4-323.2)

198.2 (140.6-349.8)

310 (125.3-494.4)

 

AC

12.6 (5.7-17.4)

25.8 (5.1-406)

588.4 (434.2-811)

TNF

SMA

71.1 (24.2-181)

2196 (1595.5-3025.5)

2219 (929.5-3606)

 

CM

192.4 (91.5-366.1)

425.6 (217.3-513.7)

876.2 (366.4-1514.5)

 

UM

72.6 (42.9-105.2)

1344 (388.2-2461)

1352 (703.7-2534.5)

 

AC

55.5 (16.3-94.7)

1265 (544.8-4435)

5857 (2437–9203)

  1. IL-10 and TNF levels were measured by ELISA in the supernatant of un-stimulated whole-blood (spontaneous production) or after LPS or PHA stimulation as described in Methods. Data are presented as median and interquartile range in pg/mL. CM, SMA, UM and AC refer to cerebral malaria, severe malarial anaemia, uncomplicated malaria and asymptomatic controls, respectively.
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Malaria Journal

ISSN: 1475-2875

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