Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka

Table 3 Comparison of median antibody levels of people with and without recent history of malaria and between the sexes (Group A- People with no history of disease within past 10 years, Group B-People with history of malaria disease within past 10 years) 293 individuals who stated ‘did not remember’ having a malaria attack were excluded in this specific analysis

	Median anti-malarial antibody levels and total IgE levels (Q1-Q3) (International Units per microlitre except IgE levels measured in ng/mL)
	Anti-AMA1_Pf	Anti-MSP1_Pf	Anti-MSP2_Pf	Anti-NANP_Pf	Total IgE	Anti- AMA1_Pv	Anti- MSP1_Pv
A (n = 532)	531.05	1450.15	1126.80	3390.35	4390.40	3356.15	2190.60
A (n = 532)	(211.96-1587.54)	(589.35-3092.42)	(516.52-2893.34)	(1878.68-6233.46)	(1850.20-8572.42)	(1407.27-9834.10)	(1113.22-5902.23)
B (n = 186)	885.10	1619.40	1492.45	4460.45	4163.30	3662.70	3559.70
B (n = 186)	(255.78-1972.92)	(603.70-3420.35)	(637.78-4450.73)	(2344.25-8624.20)	(1467.97-8258.32)	(1559.33-9297.81)	(1332.49-8794.58)
p value	0.004^*	0.239	0.027^*	0.002^*	0.405	0.405	0.003^*
Male (n = 353) (range)	592.43	1597.69	1340.89	3479.23	5719.66	3166.38	2386.78
Male (n = 353) (range)	(242.19-1701.04)	(673.87-3395.07)	(561.36-3324.04)	(2010.22-6952.50)	(2569.56-10853.45)	(1403.19-9701-93)	(1238.26-6724.18)
Female (n = 365) (range)	624.68	1501.08	1214.67	3585.46	3298.72	3691.38	2326.02
Female (n = 365) (range)	(200.56-1958.36)	(587.94-3349.18)	(519.17-3369.79)	(1913.57-6683.77)	(1189.41-5921.31)	(1591.25-10161.87)	(1122.44-6756.56)
p value	0.791	0.493	0.865	0.476	<0.001^*	0.056	0.983

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