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Table 4 Median levels of the six anti-malarial antibodies and total IgE levels in different age groups in the study population (a cross-section of the population from age >14 yrs grouped into five age groups)

From: Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka

  Median anti-malarial antibody levels and total IgE levels (Q1-Q3) (International Units per microlitre except IgE levels measured in ng/mL)
Age group MSP1_Pf MSP2_Pf AMA1_Pf NANP_Pf IgE AMA1_Pv MSP1_Pv
14-29 1319.27 1088.68 534.77 3594.79 3963.39 2766.07 2194.75
  (476.78-3107.21) (452.85-3329.50) (186.71-1918.41) (1942.41-7020.00) (1479.99-8132.72) (1202.57-8831.96) (939.18-7030.56)
30-44 1350.6 1250.91 593.89 3212.47 4291.16 3209.42 2264.82
  (614.17-3163.44) (601.21-3291.47) (203.75-1741.98) (1890.03-6015.25) (1880.78-8081.28) (1598.00-8223.37) (1245.76-5786.05)
45-59 2037.26* 1628.88 691.92 3812.24 4935.19 5174.55** 2752.59
  (948.82-4132.19) (652.23-3847.64) (283.74-1795.61) (1985.26-9252.97) (2013.94-9753.25) (2067.67-14464.98) (1471.60-8346.44)
60-75 1733.84 1128.77 592.54 3921.37 4469.11 3851.21 2670.22
  (889.44-3703.19) (564.93-2823.93) (248.00-1609.49) (2088.93-7266.04) (2106.46-6952.20) (1842.01-13399.11) (1454.50-6004.46)
>75 1729.72 1177.5 778.67 2967.53 4867.95 4677.19 1849.98
  (1287.32-3077.00) (716.23-2667.64) (325.45-1708.98) (2538.34-4836.03) (1826.49-7184.74) (2810.53-8257.18) (1125.00-4363.06)
p 0.001 0.372 0.406 0.477 0.33 p < 0.01 0.142
  1. Anti-MSP1 (Pf)* and anti-AMA1 (Pv)** levels were significantly higher in the 45–59 year age group (p = 0.001, p < 0.001 respectively – p values obtained by performing Kruskal-Wallis test for association between median antibody levels of different age groups).
  2. Q1-Q3 (1st quartile-3rd quartile).