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Table 4 Median levels of the six anti-malarial antibodies and total IgE levels in different age groups in the study population (a cross-section of the population from age >14 yrs grouped into five age groups)

From: Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka

 

Median anti-malarial antibody levels and total IgE levels (Q1-Q3) (International Units per microlitre except IgE levels measured in ng/mL)

Age group

MSP1_Pf

MSP2_Pf

AMA1_Pf

NANP_Pf

IgE

AMA1_Pv

MSP1_Pv

14-29

1319.27

1088.68

534.77

3594.79

3963.39

2766.07

2194.75

 

(476.78-3107.21)

(452.85-3329.50)

(186.71-1918.41)

(1942.41-7020.00)

(1479.99-8132.72)

(1202.57-8831.96)

(939.18-7030.56)

30-44

1350.6

1250.91

593.89

3212.47

4291.16

3209.42

2264.82

 

(614.17-3163.44)

(601.21-3291.47)

(203.75-1741.98)

(1890.03-6015.25)

(1880.78-8081.28)

(1598.00-8223.37)

(1245.76-5786.05)

45-59

2037.26*

1628.88

691.92

3812.24

4935.19

5174.55**

2752.59

 

(948.82-4132.19)

(652.23-3847.64)

(283.74-1795.61)

(1985.26-9252.97)

(2013.94-9753.25)

(2067.67-14464.98)

(1471.60-8346.44)

60-75

1733.84

1128.77

592.54

3921.37

4469.11

3851.21

2670.22

 

(889.44-3703.19)

(564.93-2823.93)

(248.00-1609.49)

(2088.93-7266.04)

(2106.46-6952.20)

(1842.01-13399.11)

(1454.50-6004.46)

>75

1729.72

1177.5

778.67

2967.53

4867.95

4677.19

1849.98

 

(1287.32-3077.00)

(716.23-2667.64)

(325.45-1708.98)

(2538.34-4836.03)

(1826.49-7184.74)

(2810.53-8257.18)

(1125.00-4363.06)

p

0.001

0.372

0.406

0.477

0.33

p < 0.01

0.142

  1. Anti-MSP1 (Pf)* and anti-AMA1 (Pv)** levels were significantly higher in the 45–59 year age group (p = 0.001, p < 0.001 respectively – p values obtained by performing Kruskal-Wallis test for association between median antibody levels of different age groups).
  2. Q1-Q3 (1st quartile-3rd quartile).