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Table 3 Factors associated with the presence of day-2 parasitaemia after treatment with mefloquine and artesunate 12 mg/kg*

From: Delayed Plasmodium falciparum clearance following artesunate-mefloquine combination therapy in Thailand, 1997–2007

Variable

Level

Day-2 parasitaemia (n)

Univariate

Multivariable

  

yes

no

OR

95% CI

OR

95% CI

Region

East

77

315

2.47

(1.77, 3.45)

4.10

(2.75, 6.12)

 

West

84

849

1.

 

1.

 

Year

1997

2

86

1.10

(1.03, 1.19)

1.27

(1.17, 1.38)

 

1998

0

37

    
 

2002

15

130

    
 

2003

31

162

    
 

2004

17

90

    
 

2005

51

230

    
 

2006

17

300

    
 

2007

28

129

    

Age

≤18

22

213

1.

 

1.

 
 

19-29

81

585

1.34

(0.82, 2.20)

1.33

(0.80, 2.20)

 

≥30

49

314

1.51

(0.89, 2.57)

1.29

(0.73, 2.28)

Parasitaemia

<10000

56

608

1.

 

1.

 

(parasites/μl)

10000-50000

83

466

1.93

(1.34, 2.77)

2.02

(1.39, 2.93)

 

>50000

22

90

2.65

(1.54, 4.56)

2.70

(1.53, 4.74)

  1. Abbreviations: OR, odds ratio; CI, confidence interval.
  2. *Results from both univariate and multivariable logistic regression are presented. Multiple imputation was used for age in the multivariable but not the univariate analyses.
  3. reference level.
  4. Year was coded as a continuous variable so the OR represents the comparison per one year increase in time.