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Table 3 Factors associated with the presence of day-2 parasitaemia after treatment with mefloquine and artesunate 12 mg/kg*

From: Delayed Plasmodium falciparum clearance following artesunate-mefloquine combination therapy in Thailand, 1997–2007

Variable Level Day-2 parasitaemia (n) Univariate Multivariable
   yes no OR 95% CI OR 95% CI
Region East 77 315 2.47 (1.77, 3.45) 4.10 (2.75, 6.12)
  West 84 849 1.   1.  
Year 1997 2 86 1.10 (1.03, 1.19) 1.27 (1.17, 1.38)
  1998 0 37     
  2002 15 130     
  2003 31 162     
  2004 17 90     
  2005 51 230     
  2006 17 300     
  2007 28 129     
Age ≤18 22 213 1.   1.  
  19-29 81 585 1.34 (0.82, 2.20) 1.33 (0.80, 2.20)
  ≥30 49 314 1.51 (0.89, 2.57) 1.29 (0.73, 2.28)
Parasitaemia <10000 56 608 1.   1.  
(parasites/μl) 10000-50000 83 466 1.93 (1.34, 2.77) 2.02 (1.39, 2.93)
  >50000 22 90 2.65 (1.54, 4.56) 2.70 (1.53, 4.74)
  1. Abbreviations: OR, odds ratio; CI, confidence interval.
  2. *Results from both univariate and multivariable logistic regression are presented. Multiple imputation was used for age in the multivariable but not the univariate analyses.
  3. reference level.
  4. Year was coded as a continuous variable so the OR represents the comparison per one year increase in time.