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Table 5 Sensitivity analysis of outcome misclassification *

From: Delayed Plasmodium falciparum clearance following artesunate-mefloquine combination therapy in Thailand, 1997–2007

 

Uncorrected

Alker 2007

Hutagalung 2005

Rogers 2009

Sensitivity

25.9

22.6

15.1

15.4

Specificity

88.5

95.0

94.6

95.1

PPV

13.5

27.8

24.2

34.3

NPV

94.6

93.4

90.6

87.0

  1. Abbreviations: PPV positive predictive value, NPV negative predictive value.
  2. *The uncorrected estimates are from this study. The relationship between day-28 PCR-uncorrected treatment failure and 42-day PCR-corrected treatment failure from three different studies was used to calculate the sensitivity, specificity, PPV, and NPV of day-2 parasitaemia as an indicator of 42-day PCR-corrected treatment failure.
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Malaria Journal

ISSN: 1475-2875

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