| |
Uncorrected
|
Alker 2007
|
Hutagalung 2005
|
Rogers 2009
|
|---|
|
Sensitivity
|
25.9
|
22.6
|
15.1
|
15.4
|
|
Specificity
|
88.5
|
95.0
|
94.6
|
95.1
|
|
PPV
|
13.5
|
27.8
|
24.2
|
34.3
|
|
NPV
|
94.6
|
93.4
|
90.6
|
87.0
|
- Abbreviations: PPV positive predictive value, NPV negative predictive value.
- *The uncorrected estimates are from this study. The relationship between day-28 PCR-uncorrected treatment failure and 42-day PCR-corrected treatment failure from three different studies was used to calculate the sensitivity, specificity, PPV, and NPV of day-2 parasitaemia as an indicator of 42-day PCR-corrected treatment failure.
