Parameter | Description |
---|---|
μ _{ IPL } | Mean of the age distribution of the initial parasite burden |
σ _{ IPL } | Standard deviation of the age distribution of the initial parasite burden |
PMF | Parasite multiplication factor (/48 h cycle) |
k _{ max } | Maximal killing rate of the drug / h |
γ | Slope of in vivo concentration-effect curve |
EC _{50} | In vivo concentration when killing rate is 50% of the maximum |