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Table 2 Median IC 50 s (with interquartile ranges) of DHA, AS, MQ and CQ against W2, D6 and 3D7 clones in the HRP-2 assay (N = 8 each)

From: Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates

IC50

DHA (nM)

AS (nM)

MQ (nM)

CQ (nM)

W2

3.8 (2.6-3.9)

4.2 (3.2-7.1)

30.4 (11.6-46.1)

336.7 (310.3-405.1)

D6

3.9 (3.8-4.3)

5.5 (3.38-7.71)

82.7 (68.2-93.0)

16.1 (6.0-18.3)

3D7

6.0 (4.6-7.3)

10.2 (5.2-11.4)

66.3 (60.8-76.1)

21.9 (10.2-28.3)

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Malaria Journal

ISSN: 1475-2875

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