Table 1 Baseline characteristics by treatment group
From: In vivo susceptibility of Plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam
Characteristics | Artesunate 2mg/kg | Artesunate 4mg/kg | DHA-Piperaquine | |||
|---|---|---|---|---|---|---|
| Â | n | (N=55) | n | (N=56) | n | (N=55) |
Age (years) | 55 | 25 (20,38) | 56 | 27 (21,35) | 55 | 27 (21,33) |
Children (< 15 years old) | 55 | 4 (7%) | 56 | 4 (7%) | 55 | 3 (5%) |
Sex | 55 | Â | 56 | Â | 55 | Â |
 Female |  | 2 (4%) |  | 2 (4%) |  | 2 (4%) |
 Male |  | 53 (96%) |  | 54 (96%) |  | 53 (96%) |
Ethnicity | 55 | Â | 56 | Â | 55 | Â |
 - Kinh (Vietnamese) |  | 26 (47%) |  | 21 (38%) |  | 19 (35%) |
 - S’tieng |  | 25 (45%) |  | 25 (45%) |  | 26 (47%) |
 - Other ethnicities |  | 4 (7%) |  | 10 (18%) |  | 10 (18%) |
Previous malaria episodes | 55 | 24 (44%) | 55 | 25 (45%) | 55 | 26 (47%) |
Febrile on admission | 55 | 55 (100%) | 56 | 51 (91%) | 55 | 47 (85%) |
Temperature ( °C) | 52 | 39.3(38.5,40.0) | 56 | 38.6 (38.0,39.7) | 55 | 39.0(37.9,39.5) |
Height (cm) | 55 | 164(160,169) | 56 | 161(158,167) | 55 | 163(158,167) |
Weight (kg) | 55 | 55(49,60) | 56 | 53(50,58) | 55 | 54(48,59) |
Parasitaemia (parasites/μL) | 55 | 27129 (12282,50868) | 56 | 29192(19415,55892) | 55 | 29390(16620,55578) |
Hematocrit (%) | 54 | 39.4(36.2,43.7) | 55 | 40.0(37.4,42.9) | 54 | 41.6(37.9,44.9) |
Hemoglobin (g/dL) | 53 | 13.8(12.6,15.4) | 53 | 14.3(13.3,15.8) | 51 | 14.2(12.9,16.0) |
White Blood Cell (x 109/L) | 53 | 5.9(4.6,7.7) | 54 | 5.6(4.4,7.2) | 53 | 6.3(5.1,8.3) |
Neutrophils (%) | 50 | 78.7(66.5,82.9) | 50 | 77.2(67.6,83.4) | 48 | 74.9(67.2,80.6) |
Lymphocytes (%) | 54 | 15.8(11.7,26.6) | 55 | 15.4(11.3,26.5) | 54 | 19.1(13.6,24.6) |
Platelets (x 109/L) | 50 | 93(69,140) | 49 | 119(79,139) | 49 | 111(70,154) |
BUN (mmol/L) | 52 | 17.1(14.5,18.2) | 55 | 16.4(14.6,18.4) | 54 | 16.6(14.3,19.1) |
Serum creatinine (μmol/L) | 53 | 79.6(61.9,88.4) | 55 | 79.6(70.7,88.4) | 54 | 79.6(70.7,88.4) |
Total Bilirubin (μmol/L) | 52 | 18.0(15.4,23.9) | 50 | 20.5(13.4,27.0) | 54 | 20.5(15.4,28.6) |
Blood glucose (mmol/L) | 52 | 4.9(4.3,6.4) | 55 | 5.2(4.7,6.4) | 54 | 5.2(4.4,6.1) |
AST (IU/L) | 53 | 35(27,49) | 55 | 40(27,50) | 54 | 40(30,58) |
ALT (IU/L) | 53 | 37(29,54) | 55 | 39(29,64) | 54 | 42(30,65) |