Table 7 Cut-off evaluation of predictive markers
From: Laboratory markers of disease severity in Plasmodium knowlesi infection: a case control study
Variable | Cut-off | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Odds of severity |
|---|---|---|---|---|---|---|
Parasite count (parasites/μl) | ≥20000 | 70.59 | 79.57 | 27.74 | 96.05 | 0.63 |
Parasite count (parasites/μl) | ≥35000 | 64.71 | 84.95 | 32.33 | 95.59 | 0.79 |
Parasite count (parasites/μl) | ≥50000 | 58.82 | 87.1 | 33.6 | 95 | 0.83 |
Parasite count (parasites/μl) | ≥100000 | 47.06 | 91.4 | 37.81 | 93.95 | 1 |
Parasite count (% IRBC) | ≥0.5 | 88.24 | 65.59 | 22.17 | 98.05 | 0.47 |
Parasite count (% IRBC) | ≥0.8 | 70.59 | 76.34 | 24.89 | 95.89 | 0.54 |
Parasite count (% IRBC) | ≥1 | 64.71 | 78.49 | 25.05 | 95.24 | 0.55 |
Parasite count (% IRBC) | ≥2 | 58.82 | 86.02 | 31.86 | 94.95 | 0.77 |
Parasite count (% IRBC) | ≥3 | 47.06 | 89.25 | 32.72 | 93.82 | 0.8 |
Platelet count (x 103 platelets/μl) | ≤60 | 88.24 | 55.91 | 18.19 | 97.72 | 0.37 |
Platelet count (x 103 platelets/μl) | ≤50 | 76.47 | 68.82 | 21.41 | 96.34 | 0.45 |
Platelet count (x 10 3 platelets/μl) | ≤45 | 70.59 | 72.04 | 21.91 | 95.66 | 0.46 |
Platelet count (x 103 platelets/μl) | ≤40 | 58.82 | 76.34 | 21.64 | 94.35 | 0.46 |