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Table 9 Shift table in CTC (Common Toxicity Criteria) grades between Day 0–7 and Day 0-28

From: Anti-malarial drug safety information obtained through routine monitoring in a rural district of South-Western Senegal

  D7 D28
DO CTC Grade Grade 0 Grade 1 Grade 2 Grade 3 Total Grade 0 Grade 1 Grade 2 Grade 3 Total
WCC CTC Grade Grade 0 92 5 2 3 102 70 7 0 1 78
Grade 1 5 2 1 0 8 4 1 0 0 5
Grade 2 4 1 1 0 6 2 0 1 1 4
Grade 3 0 0 1 0 1 0 0 0 0 0
total 101 8 5 3 117 76 8 1 2 87
AST CTC Grade Grade 0 103 31 11 1 146 76 41 12 0 129
Grade 1 11 14 6 1 32 3 6 9 1 19
Grade 2 0 0 2 0 2 1 0 0 0 1
Grade 3 0 0 1 0 1 0 0 0 0 0
total 114 45 20 2 181 80 47 21 1 149
ALT CTC Grade Grade 0 141 29 1 0 171 113 29 1 0 143
Grade 1 4 5 1 0 10 1 3 0 0 4
Grade 2 0 0 0 0 0 0 1 0 0 1
Grade 3 0 1 0 0 1 0 0 0 0 0
total 145 35 2 0 182 114 33 1 0 148
Creatinine CTC Grade Grade 0 53 13 0 0 66 36 14 0 0 50
Grade 1 7 4 0 0 11 7 1 0 0 8
Grade 2 0 0 0 0   0 0 0 0 0
Grade 3 0 0 0 0   0 0   0 0
total 60 17 0 0 77 43 15 0 0 58
Bilirubin CTC Grade Grade 0 82 7 1 1 91 42 5 3 1 51
Grade 1 0 0 0 0 0 1 0 0 0 1
Grade 2 0 0 0 0 0 2 0 1 0 3
total 82 7 1 1 91 45 5 3 1 54