Table 4 Subjects with QTc >60 ms from baseline based on different QT correction formulae
Age (yrs) | Sex | Drug | QTc day 0 (ms) | QTc day 3 (ms) | Δ QTc(day3-day0) | DEAQ (ng/ml) |
|---|---|---|---|---|---|---|
3.5 | Male | A-A | 361B | 413B | 52 | 109 |
315F | 379F | 64 | ||||
373H | 390H | 17 | ||||
5.5 | Female | A-A | 353B | 399B | 46 | 162 |
310F | 386F | 76 | ||||
363H | 385H | 22 | ||||
6.0 | Female | A-A | 404B | 464B | 60 | 0 |
357F | 426F | 69 | ||||
394H | 430H | 36 | ||||
6.5 | Male | A-A | 361B | 443B | 82 | 241 |
315F | 397F | 82 | ||||
373H | 416H | 43 | ||||
9.0 | Male | A-L | 366B | 443B | 77 | NA |
335F | 413F | 78 | ||||
355H | 414H | 59 | ||||
10.0 | Female | A-L | 387B | 450B | 63 | NA |
347F | 418F | 71 | ||||
376H | 419H | 43 |