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Table 1 Summary of the impact of combination therapy, MFT and sequential application on useful therapeutic life and the spread of multi-resistant genotypes assuming drug usage typical in control scenarios

From: Policy options for deploying anti-malarial drugs in endemic countries: a population genetics approach

Policy

Impact

Sequential application

Medium useful therapeutic life

 

Low multi-drug resistance

MFT

Long useful therapeutic life

 

Low multi-drug resistance

Combination therapy

Longest useful therapeutic life

 

Extreme increase in multi-drug resistance