Polymorphism

Genotype

Cerebral malaria n = 65

Uncomplicated malaria n = 52

p value

OR

95% CI


Δ22

W/W

36(56.3)

18(35.3)

.025^{I}

0.42

0.200.98


W/D

21(32.8)

30(58.8)^{II}

.005^{III}

0.34

0.160.73


D/D

7(10.9)

3(5.9)
   
GT_{n}

SM

12(19.4)

8(16.7)
   

MM

46(74.2)

34(70.8)
   

ML

4(6.4)

6(12.5)
   
 OR and 95% CI presented only for p values where p < 0.05
 ^{I} p value for dominant genotype test, WD/DD vs WW
 ^{II}p = 0.065 for Hardy Weinberg Test of equilibrium, excess of heterozygotes
 ^{III} p value for heterozygote advantage genotype test, WD vs DD/WW