|
Polymorphism
|
Genotype
|
Cerebral malaria n = 65
|
Uncomplicated malaria n = 52
|
p value
|
OR
|
95% CI
|
|---|
|
Δ22
|
W/W
|
36(56.3)
|
18(35.3)
|
.025I
|
0.42
|
0.20-0.98
|
| |
W/D
|
21(32.8)
|
30(58.8)II
|
.005III
|
0.34
|
0.16-0.73
|
| |
D/D
|
7(10.9)
|
3(5.9)
| | | |
|
GTn
|
SM
|
12(19.4)
|
8(16.7)
| | | |
| |
MM
|
46(74.2)
|
34(70.8)
| | | |
| |
ML
|
4(6.4)
|
6(12.5)
| | | |
- OR and 95% CI presented only for p values where p < 0.05
- I p value for dominant genotype test, WD/DD vs WW
- IIp = 0.065 for Hardy Weinberg Test of equilibrium, excess of heterozygotes
- III p value for heterozygote advantage genotype test, WD vs DD/WW
