Table 5 Haplotype associations of MASP2 and CFP2 genes for placental malaria
From: Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria
Gene area | Overall p-value1 | Specific haplotype | Prevalence in cases | Prevalence in controls | P- value2 |
|---|---|---|---|---|---|
MASP2, exon 11 | |||||
rs2273347-rs2273346 | 0.05 | AAGTA | 0.12 | 0.19 | 0.021 |
MASP2, 5' end | |||||
rs3765900-rs56392418-R99Q | 0.05 | TGG | 0.53 | 0.21 | 0.0051 |
CFP | |||||
rs1048118-rs8177079-rs909523 | 0.028 | ATA | 0.08 | 0.15 | 0.007 |