Table 2 Characterization of the four QN-resistant isolates of Plasmodium falciparum
| Â | SK20 | SK22 | MR2 | KB12 |
|---|---|---|---|---|
Origin | Srisaket | Srisaket | Chantaburi | Kanchanaburi |
QN IC50 (nM) | 521.8 | 503.0 | 530.6 | 654.4 |
Pfmdr1 mutations | ||||
   N86Y | N | N | N | N |
   Y184F | F | F | F | F |
   S1034C | S | S | S | C |
   N1042D | N | N | N | D |
   D1246Y | D | D | D | D |
Pfmdr1 copy number | 0.8 | 0.9 | 1.2 | 2.0 |
Pfnhe-1 | ||||
   DNNND repeats | 3 | 4 | 1 | 3 |
   DDNNNDNHNDD repeats | 1 | 2 | 1 | 1 |
   NHNDNHNNDDD repeats | 1 | 1 | 0 | 1 |