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Table 4 Predicted equilibrium parasite densities required to maintain a positive RDT test

From: Modelling the dynamics of Plasmodium falciparum histidine-rich protein 2 in human malaria to better understand malaria rapid diagnostic test performance

Product

Min. detectable Pf HRP2 conc. (ng/mL)

Est. no. parasites for MinCM (parasites/μL)

Est. no. parasites for MaxCM (parasites/μL)

Firstsign™ - ParaView (Pan + Pf) Malaria Test

27.75

64.9

29.6

SD BIOLINE Malaria Ag Pf/Pv

6.94

16.7

7.8

Carestart™ Malaria HRP2/pLDH

6.94

16.7

7.8

ICT Malaria Combo Cassette Test

13.88*

32.8

15.1

  1. * The lowest dilution which gives a band intensity > 1 to adjust for false positive result on negative control.
  2. MinCM and MaxCM represent the minimum circulating model and maximum circulating model, respectively.
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Malaria Journal

ISSN: 1475-2875

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