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Table 2 Comparison of different parameters between severe malaria cases who survived and those who died in ICU

From: Severe imported malaria in an intensive care unit: a review of 59 cases

  Survivors (n = 50) Non-survivors (n = 9) P*
Age [median IQR] 42 (33-49) 45 (33-57) 0,353
Male gender [n (%)] 38 (76.0) 9 (100) 0.161
Duration of symptoms [median IQR] 7 (4-9) 6 (4-8) 0.828
Time since arrival to diagnosis [median IQR] 8 (6-15) 16 (10-20) 0.027
Non-immune (vs semi-immune) status [n (%)] 24/46(52.2) 5/8 (62.5) 0.711
Parasitaemia [n (%)] 15 (30.3) 2 (22.2) 0.252
   ≤10 19 (38.0) 3 (33.3)  
   11-50 4 (8.0) 3 (33.3)  
   > 50 12 (24.4) 1 (11.1)  
   Non quantified    
SAPS II [median (IQR)] 28.5 (21.5-37) 68 (47-73) < 0.001
Glasgow coma scale [n (%)] ≥13 33 (68.8) (22.2) 0.019
10-12 (rousable coma) 8 (16.7) 3 (33.3)  
≤ 9 (unrousable coma) 7 (14.6) 4 (44.4)  
Haemoglobin (mg/dL) [median (IQR)] 9.5 (8.0-12.6) 10.4 (8.3-12.2) 0.618
Renal failure [n (%)] 23 (46.0) 8 (88.9) 0.027
Pulmonary oedema/ARDS [n (%)] 14 (29.2) 8 (88.9) < 0.001
Hypoglycaemia [n (%)] 11 (22.4) 7 (77.8) 0.002
Circulatory collapse, shock [n (%)] 22 (44.9) 7 (77.8) 0.080
Abnormal bleeding/DIC [n (%)] 6 (13.6) 5 (62.5) 0.007
Acidaemia/acidosis [n (%)] 14 (29.8) 9 (100) < 0.001
WHO major criteria of severe malaria ≥ 5 [n (%)] 20 (40.0) 9 (100) < 0.001
Malaria Prediction Score (MPS)ref [median (IQR)] 1.78 (0.38-4.53) 4.68 (4.21-5.20) 0.008
Malaria Score for Adults (MAS)ref [median (IQR)] 3 (1-7) 9 (6-10) 0.001
Length of stay in ICU [median (IQR)] 4 (2-12) 8 (3-27) 0.185
  1. * χ2 test or Fisher exact test for categorical variables, Wilcoxon test for continuous variables. IQR = interquartile ranges