Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Prevalences of pfmdr1 and pfcrt SNPs in Fukayosi village, Bagamoyo District, Tanzania, from 2004-2011

From: Temporal trends of molecular markers associated with artemether-lumefantrine tolerance/resistance in Bagamoyo district, Tanzania

Gene Mutation Study 1 Study 2 Study 3 Study 4 Study 5 Study 6
   2004 2006 2007 2008 2010 2011
   n= (%) n= (%) n= (%) n= (%) n= (%) n= (%)
pfmdr1 N86 27 26.5 7 14 94 36.6 115 61.1 23 74.2 76 61.3
  mix-86 30 29.4 19 38 71 27.6 27 14.4 3 9.7 20 16.1
  86Y 45 44.1 24 48 92 35.8 46 24.5 5 16.1 28 22.6
  184F 8 8 7 14 61 23.9 46 24.7 10 32.3 44 34.9
  mix-184 17 17 6 12 30 11.8 23 12.4 8 25.8 15 11.9
  Y184 75 75 37 74 164 64.3 117 62.9 13 41.9 67 53.2
  D1246 50 51 26 54.2 202 79.8 158 85.9 27 84.4 106 84.8
  mix-1246 24 24.5 14 29.2 20 7.9 15 8.1 4 12.5 14 11.2
  1246Y 24 24.5 8 16.7 31 12.3 11 6 1 3.1 5 4
pfcrt K76 26 25.5 24 49 167 65 128 68.4 23 74.2 104 84.6
  mix-76 23 22.5 11 22.5 43 16.7 28 15 2 6.5 5 4.1
  76T 53 52 14 28.6 47 18.3 31 16.6 6 19.4 14 11.4
  1. N = asparagine, Y = tyrosine, F = phenylalanine, D = aspartic acid, mix = the presence of both alleles at one loci.