Table 2 Prevalences of pfmdr1 and pfcrt SNPs in Fukayosi village, Bagamoyo District, Tanzania, from 2004-2011
Gene | Mutation | Study 1 | Study 2 | Study 3 | Study 4 | Study 5 | Study 6 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2004 | 2006 | 2007 | 2008 | 2010 | 2011 | ||||||||
n= | (%) | n= | (%) | n= | (%) | n= | (%) | n= | (%) | n= | (%) | ||
pfmdr1 | N86 | 27 | 26.5 | 7 | 14 | 94 | 36.6 | 115 | 61.1 | 23 | 74.2 | 76 | 61.3 |
mix-86 | 30 | 29.4 | 19 | 38 | 71 | 27.6 | 27 | 14.4 | 3 | 9.7 | 20 | 16.1 | |
86Y | 45 | 44.1 | 24 | 48 | 92 | 35.8 | 46 | 24.5 | 5 | 16.1 | 28 | 22.6 | |
184F | 8 | 8 | 7 | 14 | 61 | 23.9 | 46 | 24.7 | 10 | 32.3 | 44 | 34.9 | |
mix-184 | 17 | 17 | 6 | 12 | 30 | 11.8 | 23 | 12.4 | 8 | 25.8 | 15 | 11.9 | |
Y184 | 75 | 75 | 37 | 74 | 164 | 64.3 | 117 | 62.9 | 13 | 41.9 | 67 | 53.2 | |
D1246 | 50 | 51 | 26 | 54.2 | 202 | 79.8 | 158 | 85.9 | 27 | 84.4 | 106 | 84.8 | |
mix-1246 | 24 | 24.5 | 14 | 29.2 | 20 | 7.9 | 15 | 8.1 | 4 | 12.5 | 14 | 11.2 | |
1246Y | 24 | 24.5 | 8 | 16.7 | 31 | 12.3 | 11 | 6 | 1 | 3.1 | 5 | 4 | |
pfcrt | K76 | 26 | 25.5 | 24 | 49 | 167 | 65 | 128 | 68.4 | 23 | 74.2 | 104 | 84.6 |
mix-76 | 23 | 22.5 | 11 | 22.5 | 43 | 16.7 | 28 | 15 | 2 | 6.5 | 5 | 4.1 | |
76T | 53 | 52 | 14 | 28.6 | 47 | 18.3 | 31 | 16.6 | 6 | 19.4 | 14 | 11.4 | |