|
Microsatellites
|
Sampled populations - Miyobo
|
Sampled populations - Ngonamanga
|
|---|
|
Single mutant
|
Double mutant
|
Triple mutant
|
All samples
|
Triple mutant
|
|---|
|
( N=10)
|
(N=37)
|
(N=17)
|
(N=64)
|
(N=82)
|
|---|
|
R
s
|
H
e
|
R
s
|
H
e
|
R
s
|
H
e
|
R
s
|
H
e
|
F
ST
|
P
|
R
s
|
H
e
|
|---|
|
Loci
flanking
dhfr
gene
|
Dhfr 0.3
|
3
|
0.51
|
3
|
0.32
|
2
|
0.15
|
3
|
0.33
|
0.02
|
NS
|
7
|
0.26
|
|
Dhfr 4.4
|
1
|
0.00
|
2
|
0.14
|
2
|
0.17
|
2
|
0.10
|
-0.04
|
NS
|
3
|
0.10
|
|
Dhfr 5.3
|
3
|
0.56
|
2
|
0.18
|
1
|
0.00
|
2
|
0.24
|
0.10
|
0.03
|
3
|
0.08
|
|
All loci
|
2
|
0.36
|
2
|
0.21
|
2
|
0.11
|
2
|
0.22
|
0.03
|
0.05
|
4
|
0.15
|
|
Neutral
loci
|
TA1
|
4
|
0.82
|
5
|
0.83
|
6
|
0.89
|
6
|
0.85
|
0.04
|
0.04
|
12
|
0.87
|
|
TA102
|
4
|
0.64
|
7
|
0.88
|
5
|
0.84
|
6
|
0.79
|
0.03
|
NS
|
8
|
0.78
|
|
ARA2
|
4
|
0.69
|
5
|
0.77
|
6
|
0.79
|
5
|
0.75
|
-0.03
|
NS
|
9
|
0.81
|
|
TA87
|
4
|
0.87
|
6
|
0.85
|
5
|
0.81
|
6
|
0.84
|
0.01
|
NS
|
9
|
0.84
|
|
PfPK2
|
5
|
0.93
|
6
|
0.86
|
5
|
0.85
|
6
|
0.88
|
-0.03
|
NS
|
12
|
0.87
|
|
TA81
|
4
|
0.87
|
5
|
0.81
|
4
|
0.71
|
5
|
0.80
|
-0.04
|
NS
|
10
|
0.87
|
|
TA42
|
3
|
0.60
|
2
|
0.11
|
2
|
0.28
|
2
|
0.32
|
0.06
|
NS
|
8
|
0.36
|
|
Pfg377
|
3
|
0.67
|
3
|
0.56
|
3
|
0.65
|
3
|
0.62
|
-0.04
|
NS
|
7
|
0.55
|
|
TA109
|
5
|
0.86
|
5
|
0.80
|
4
|
0.79
|
5
|
0.82
|
0.04
|
0.03
|
8
|
0.75
|
| |
All loci
|
4
|
0.77
|
5
|
0.72
|
4
|
0.73
|
5
|
0.74
|
<0.01
|
NS
|
9
|
0.74
|
- N: number of isolates genotyped, He: expected heterozygosity; Rs: allelic richness. All loci: mean over loci Rs and He and global Fst over loci as calculated by FSTAT. P: P- values of permutation tests to assess significance of Fst values. NS: non-significant (P>0.05).
