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Table 3 Statistics of the 15 STR loci of Plasmodium falciparum -positive individuals: mutants to SFX

From: Genetic diversity and signatures of selection of drug resistance in Plasmodium populations from both human and mosquito hosts in continental Equatorial Guinea

Microsatellites Sampled populations - Miyobo Sampled populations - Ngonamanga
Single mutant Double mutant All samples ( N=60) Double mutant Triple mutant All samples (N=85)
    (N=63) (N=22)  
(N=17) ( N=43)  
R s H e R s H e R s H e F ST P R s H e R s H e R s H e F ST P
Loci flanking dhps gene Dhps 0.8 4 0.60 5 0.75 5 0.67 0.02 NS 9 0.81 5 0.64 9 0.73 0.06 0.01
Dhps 4.3 6 0.83 5 0.77 6 0.80 <0.01 NS 7 0.78 4 0.71 7 0.75 0.13 <0.01
Dhps 7.7 6 0.79 7 0.84 8 0.82 0.09 <0.01 10 0.85 6 0.67 10 0.76 0.14 <0.01
All loci 5 0.74 6 0.79 6 0.76 0.04 <0.01 9 0.81 5 0.67 9 0.74 0.11 <0.01
Neutral loci TA1 5 0.79 8 0.87 8 0.83 0.04 NS 9 086 8 0.88 9 0.87 <0.01 NS
TA102 5 0.78 9 0.87 9 0.83 0.04 0.01 6 0.75 7 0.86 7 0.80 <-0.01 NS
ARA2 6 0.79 6 0.69 7 0.74 0.06 <0.01 7 0.80 6 0.82 7 0.81 -0.01 NS
TA87 5 0.79 8 0.84 7 0.82 0.05 0.02 8 0.83 7 0.87 8 0.85 0.02 NS
PfPK2 5 0.83 8 0.80 8 0.81 0.11 0.02 10 0.87 8 0.87 11 0.87 0.02 <0.05
TA81 5 0.77 6 0.78 7 0.78 -0.02 NS 9 0.88 8 0.83 9 0.85 <0.01 NS
TA42 1 0.00 4 0.29 3 0.14 0.03 NS 5 0.44 3 0.18 5 0.31 0.05 0.04
Pfg377 3 0.56 4 0.59 3 0.57 <-0.01 NS 5 0.59 3 0.40 5 0.50 0.01 NS
TA109 6 0.86 6 0.81 6 0.83 -0.02 NS 5 0.72 5 0.60 6 0.66 0.16 <0.01
  All loci 5 0.69 6 0.73 6 0.71 0.03 <0.01 7 0.75 6 0.70 7 0.72 0.03 0.01
  1. N: number of isolates genotyped, He: expected heterozygosity; Rs: allelic richness. All loci: mean over loci Rs and He and global Fst over loci as calculated by FSTAT. P: P- values of permutation tests to assess significance of Fst values. NS: non-significant (P>0.05).