Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi

Malaria Journal

Table 1 Sex ratio and survival of driver transgenic lines carrying the Aedes aegypti Act-4 promoter (OX3545 construct)

G₀	G₁	G₂
Lines outcrossed with wild-type	Transgenic adults	Wild type larvae	Transgenic larvae	Transgenic adults*
Lines outcrossed with wild-type	Transgenic adults	Wild type larvae	Transgenic larvae	Females	Males
DAa-1 ♂	1 ♂	325	199	0	17
DAa-2 ♂	4 ♂	680	138	21	22
DAa-3 ♂	1 ♂	200	86	3	29
DAa-4 ♂	17 ♂	1140	659	31	134
DAa-5 ♂	4 ♂	90	45	3	11
DAa-6 ♀	1 ♂	70	44	22	9
DAa-7 ♀	1 ♂	100	45	9	15
DAa-8 ♀	1 ♂	90	30	10	17
DAa-9 ♂	1 ♂, 2 ♀	0	0	0	0
DAa-10 ♂	1 ♂	0	0	0	0
DAa-11 ♂	2 ♂	0	0	0	0
DAa-12 ♂	1 ♂	0	0	0	0
DAa-13 ♂	2 ♂	0	0	0	0
DAa-14 ♂	1 ♂	0	0	0	0
DAa-15 ♂	1 ♀	0	0	0	0

*A flightless phenotype was not observed in males or females. An expanded Table showing results of five generations is provided as Additional file 2: Table S1.

ISSN: 1475-2875