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Table 5 Effects of tetracycline on survival and flightless phenotype of transgenic Anopheles stephensi carrying driver and effector transgenes

From: Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi

♂ driver lines outcrossed with ♀ effector line E-1 Tetracycline concentration Larvae Transgenic adults
   Only one transgene Effector + driver transgenes Flying females Flightless females Flying males Totals (% survival larvae-adult)
DAa-3 10 μg/ml 2535 371 108 16 226 350 (94%)
DAa-3 5 μg/ml 930 269 37 3 91 131 (49%)
DAa-3 1 μg/ml 610 143 21 10 69 100 (70%)
DAa-3 100 ng/ml 750 162 15 16 61 92 (57%)
DAa-3 10 ng/ml 600 127 9 28 38 75 (59%)
DAs-21 10 μg/ml nd 233 25 18 82 125 (54%)
DAs-22 10 μg/ml nd 628 155 12 285 (1)* 453 (72%)
  1. *One flightless male was observed among the progeny of driver DAs-22 ♂ x effector E-1 ♀ cross (indicated in parenthesis).