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Table 4 Prevalence of mutations conferring resistance to CQ and SP in Plasmodium falciparum according age

From: Prevalence of the molecular marker of Plasmodium falciparum resistance to chloroquine and sulphadoxine/pyrimethamine in Benin seven years after the change of malaria treatment policy

Molecular marker

Symptomatic

Asymptomatic

< 10 ans

≥ 10 ans

< 10 ans

≥ 10 ans

T 76

53 (94.6%)

15 (93.8%)

74 (91.4%)

58 (96.7%)

Y86

25 (45.5%)

4 (25%)*

49 (60.5%)

43 (71.7%)

T76 + Y86

24 (43.6%)

4 (25%)**

47 (58.8%)

42 (70%)

G437

36 (64.3%)

12 (70.6%)

54 (68.4%)

48 (82.8%)

E540

0%

0%

0%

0%

I51

52 (92.9%)

17 (100)

77 (96.2%)

58 (98.3%)

R59

53 (94.6%)

16 (94.1%)

77 (96.2%)

53 (89.8%)

N108

54 (96.4%)

17 (100)

78 (97.5%)

58 (98.3%)

IRN1

51 (91.1%)

16 (94.1%)

76 (95%)

51 (86.4%)

IRNG2

33 (58.9%)

11 (64.7%)

52 (65.8%)

42 (72.4%)

  1. 1pfdhfr triple mutants: (I51, R59, and N108).
  2. 2pfdhfr/pfdhps quadruple mutants: (pfdhfr I51, R59, N108 and pfdhps G437).
  3. *p = 0.16 (fisher test).
  4. **p = 0.24 (fisher test).