Table 3 Confidence interval from log transformed data for Bioequivalence assessment
Pharmacokinetic parameters | Ratio of Artefan® to Coartem® (%) | 90% Confidence interval of the geometric mean ratio | Acceptance criteria | P-value (normal) |
|---|---|---|---|---|
LnCmax | 84.0 | 49 - 143% | 80 - 125% | 0.559 |
LnAUC0-168 | 84.5 | 53 - 137% | 80 - 125% | 0.538 |
LnAUC0-∞ | 84.3 | 52 - 135% | 80 - 125% | 0.575 |