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Table 1 Microemulsion systems tested

From: Determination of artemether and lumefantrine in anti-malarial fixed-dose combination tablets by microemulsion electrokinetic chromatography with short-end injection procedure

Composition of the ME Current developed, RT and migration order
a) 0.81% w/w octane + 6.61% w/w 1-butanol + 3.31% w/w SDS + 89.27% w/w 10 mM borate buffer + 70 μA; RT around 12 min; MTartemether < MTlumefantrine;
b) 0.81% w/w octane + 6.61% w/w 1-butanol + 3.31% w/w SDS + 89.27% w/w 20 mM borate buffer + 85 μA; RT around 15 min; MTartemether < MTlumefantrine;
c) 0.81% w/w octane + 6.61% w/w 1-butanol + 3.31% w/w LiDS + 89.27% w/w 10 mM borate buffer + 60 μA; RT around 10 min; MTartemether < MTlumefantrine;
d) 0.8% w/w octane + 6.6% w/w 1-butanol + 6.0% w/w SDS + 20% w/w isopropanol + 66.6% w/w 25 mM phosphate buffer +67 μA; RT around 9 min; MTartemether > MTlumefantrine; baseline disturbance
  1. Operating conditions: silica capillary, 30 cm (20 cm to the detector); injection 4 nL; separation voltage 15 kV (normal polarity); 25°C; λ = 214 nm.