Figure 3
Observed plasma concentrations of artemether (left panels) and dihydroartemisinin (right panels) after administration of 6 × 20 = 120 mg (children) and 6 × 80 = 480 mg (adults) artemether in 135 Tanzanian patients. The solid lines represent the mean population prediction and the dotted lines 95% prediction intervals. Triangles and squares represent residual plasma concentrations of lumefantrine and desbutyl-lumefantrine found prior treatment initiation.