Direct comparison of IC
values obtained using the HRP-2 and MSF assays. (A) IC50s of reference laboratory clones (WBCs absent). Median IC50 values for each drug against W2, D6, 3D7 and K1 strains are indicated using different symbols/colours (n = number of IC50 values attained for each strain from 3–5 experiments). (B) IEV IC50s of field isolates (WBCs present). Of the total 41 IEV isolates evaluated in both the HRP-2 and MSF assays, IC50 values were obtained for both assays in 15 isolates. Median IC50 values for field isolates obtained by HRP-2 and MSF assays are shown as black circles and red squares, respectively. Significant p-values of Wilcoxon matched pair tests comparing IC50s from HRP-2 and MSF assays and their mean differences are designated with * symbol. NS signifies no statistical significance.