Table 2 Clinical and parasitological response rates for artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) using per protocol analysis, western Kenya 2011
Outcome | AL | DP | p-value |
|---|---|---|---|
% (95% CI) | % (95% CI) | ||
Early treatment failure | 0% (0%–3%) (0/137) | 0% (0%–3%) (0/137) | 1 |
Day 3 parasite clearance | 99% (96%–99%) (130/131) | 100% (97%–100%) (126/126) | 0.34 |
Day 28 PCR-uncorrected ACPR * | 61% (52%–70%) (71/116) | 83% (75%–89%) (96/116) | 0.001 |
Day 28 PCR-corrected ACPR ** | 97% (92%–99%) (105/108) | 99% (95%–100%) (114/115) | 0.48 |
Day 42 PCR-uncorrected ACPR | 44% (35%–54%) (49/111) | 54% (45%–63%) (61/113) | 0.14 |
Day 42 PCR-corrected ACPR | 96% (90%–99%) (97/101) | 96% (91%–99%) (105/109) | 0.26 |