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Table 3 Histopathological changes in the brains of fatal CM and NCM patients

From: Nuclear factor kappa B modulates apoptosis in the brain endothelial cells and intravascular leukocytes of fatal cerebral malaria

Histopathological changes

Code no.

Group

aPRBC sequestration

bRing haemorrhage

cDurck’s granuloma

Total score

A001

CM

5

1

0

6

A002

CM

5

3

0

8

A003

CM

3

0

0

3

A004

CM

1

3

1

5

A005

CM

1

1

0

2

A006

CM

5

1

0

6

A007

CM

5

0

0

5

A008

CM

1

0

2

3

A009

CM

1

0

1

2

A101

NCM

0

0

0

0

A102

NCM

0

0

0

0

  1. aPRBC sequestration range: 0 to 5 points, bRing haemorrhage range: 0 to 3 points, cDurck’s granuloma range: 0 to 2 points.
  2. Total score range: 0 to 10 points. A score of 0 signifies no abnormal histopathological changes, while a score of 10 signifies the most severe histopathological changes.