Figure 3From: Azadirachta indica ethanolic extract protects neurons from apoptosis and mitigates brain swelling in experimental cerebral malariaFas and Fas ligand expression. A. Micrographs showing the expression of Fas in pyramidal neurons of representative examples of (from left): an uninfected mouse, an untreated Plasmodium berghei-infected mouse (inf.), and a P. berghei-infected mouse treated with Azadirachta indica crude extract. B. Effect of A. indica on the expression of Fas (upper) and Fas ligand (lower) in pyramidal neurons of P. berghei-infected mice. Note the significant decrease in expression of both molecules following treatment with chloroquine (chlor.), artemether (artem.), and A. indica extract (more marked at dose 1,000 mg/kg). Data are mean ± SEM.Back to article page