Serological responses to a soluble recombinant chimeric Plasmodium vivax circumsporozoite protein in VK210 and VK247 population

Table 1 Prevalence (% positive), 95% confidence intervals, and MFI values of IgG responses to rPvCSP-c in sera typed VK210 and VK247 vivax malaria patients and healthy individuals

Type group	No. of patients samples (n)			95% CI (%)^b	MFI
Type group	Positive	Negative	Total (%)^a	95% CI (%)^b	MFI
VK210	75	31	106 (70.8)	61.5–78.6	5883
VK247	8	8	8 (100)	67.6.1–100	11198
Total	83	31	114 (72.8)	64.0–80.1	6256
Type group	No. of healthy samples ( n )			95% CI (%) ^d	MFI
Type group	Positive	Negative	Total (%) ^c	95% CI (%) ^d	MFI
Total	3	77	80 (3.8)	89.6–98.7	989

^aSensitivity: % of Positive in patient samples.
^bConfidence intervals.
^cSpecificity: % of Negative in healthy samples.
^dDifferences in the total IgG prevalence for each antigen between vivax patients and healthy individuals were calculated with Student’s-t test. P < 0.05 considered as statistically significant.
MFI mean fluorescence intensity.

ISSN: 1475-2875