Skip to main content

Table 3 Correlation between clinical signs of hypovolaemia and invasive haemodynamic measures

From: The reliability of the physical examination to guide fluid therapy in adults with severe falciparum malaria: an observational study

  

Number of observations

GEDVI1

CI2

ELWI3

  

mean (95% CI)

mean (95% CI)

mean (95% CI)

Mucous membranes

Normal

132

572 (548 – 595)

3.57 (3.43 – 3.71)

9.6 (8.9 – 10.3)

Dry

297

562 (548 – 576)

3.42 (3.34 – 3.51)

9.8 (9.4 – 10.1)

Axillae

Moist

253

571 (556–585)

3.47 (3.38 -3.57)

9.4 (9.0 -9.8)

Dry

177

556 (536–576)

3.46 (3.35 – 3.56)

10.1 (9.6 -10.7)

Tissue turgor

Normal

409

560 (548 – 573)

3.5 (3.43 - 3.57)

9.7 (9.3- 10.0)

Decreased

21

643 (602 – 684)ɸ

2.83 (2.59 - 3.07) ɸ

10.8 (9.3 – 12.2)

Capillary return*

Normal

371

566 (554–579)

3.52 (3.45 -3.59)

9.5 (9.2 – 9.9)

Reduced

30

504 (473–534) ɸ

2.84 (2.54 -3.14) ɸ

9.9 (8.4 – 11.5)

Heart rate*

<100 bpm

269

575 (560 – 590)

3.43 (3.36 – 3.51)

9.3 (8.8 - 9.7)

≥100 bpm

150

543 (524 – 562) ɸ

3.51 (3.38 – 3.65)

10.0 (9.5 – 10.5) ɸ

Heart rate*

<120 bpm

387

565 (552 – 578)

3.48 (3.41 – 3.55)

9.4 (9.1 – 9.7)

≥120 bpm

32

528 (497 – 560)

3.3 (2.93 - 3.66)Ʊ

11.4 (10.2 - 12.7) ɸ

  1. 1 Global end-diastolic volume index.
  2. 2 Cardiac index.
  3. 3 Extravascular lung water index.
  4. * In the absence of inotropic therapy.
  5. ɸ p < 0.01 for a difference.
  6. Ʊ p < 0.05 for a difference.