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Table 2 Trends in molecular genotypes and in vitro susceptibility for P. falciparum isolates

From: Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000–2011

Slopes of prevalence in Pfcrt76T
  2000-2011 2004-2011
Slope (95% CI) P value Slope (95% CI) P value
Senegal −0.167 [−0.209; -0.125] <10-3 −0.182 [−0.264; -0.102] <10-3
Mali −0.009 [−0.052; 0.034] 0.72 −0.102 [−0.178; -0.027] 0.03
Ivory Coast −0.146 [−0.183; -0.111] <10-3 −0.265 [−0.325; -0.207] <10-3
Cameroon −0.090 [−0.130; -0.050] <10-3 −0.106 [−0.172; -0.041] <10-3
Slopes of IC 50 values for CQ
Senegal −0.081 [−0.130; -0.032] <10-3 −0.123 [−0.220; -0.026] <10-3
Mali −0.042 [−0.090; 0.007] 0.02 −0.098 [−0.167; -0.030] <10-3
Ivory Coast −0.057 [−0.093; -0.021] <10-3 −0.120 [−0.177; -0.063] <10-3
Cameroon −0.055 [−0.089; -0.020] <10-3 −0.100 [−0.154; -0.046] <10-3
  1. Slopes of prevalence in Pfcrt76T and slopes of IC50 values from patients returning to France from Senegal, Mali, Ivory Coast, and Cameroon, between 2000–2011 and 2004–2011 (after CQ withdrawal).