Skip to main content

Table 1 Medians [95% confidence intervals] of plasma cytokine levels and their differences in immunized mice before and during first pregnancy

From: Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria

Cytokine

Nulligravidae (N = 34)

Primigravidae (N = 84)

Difference

P(T)1

IL-5 (pg/mL)

695 [423–942]

726 [548–877]

13 [-250–217]

0.9

IL-10 (pg/mL)

61 [46–85]

72 [61–91]

-20 [-48–0]

0.06

IL-12 (ng/mL)

13.0 [7.9–20.6]

17.0 [10.0–21.2]

0.2 [-2.9–4.3]

0.9

IL-13 (pg/mL)

19.9 [0–66.7]

7.8 [0–59.6]

0 [0–14.6]

0.6

IFN-γ (ng/mL)

8.5 [5.5–9.8]

8.8 [7.2–9.5]

0.2 [-0.9–1.5]

0.8

TNF (pg/mL)

22.3 [0.3–68.0]

20.0 [7.3–36.6]

0 [-8.4–15.8]

0.9

  1. 1The statistical significance of the difference between nulligravid and primigravid mice in median cytokine levels.