Table 3 Biology data in 553 patients treated with atovaquone-proguanil for imported uncomplicated malaria
Diagnosis | Day 3 | Day 7 | Day 30 | |
|---|---|---|---|---|
Haemoglobin (g/dL) | N (%) | N (%) | N (%) | N (%) |
≤8 | 11 (1.9) | 16 (3.4) | 4 (1.1) | 0 |
8.1-10 | 28 (5.1) | 55 (11,7) | 48 (13.2) | 17 (6.4) |
10.1-12 | 136 (24.6) | 162 (34.6) | 126 (34.6) | 73 (27.6) |
>12 | 378 (68.4) | 236 (50.3) | 186 (51,1) | 175 (66.0) |
Platelets count (per mm 3 ) | ||||
≤20,000 | 8 (1.4) | 4 (0.8) | 0 | 0 |
20,001-50,000 | 43 (7.8) | 14 (3.0) | 1 (0.3) | 0 |
50,001-100,000 | 173(31.3) | 102 (21.8) | 1 (0.3) | 0 |
100,001-150,000 | 160 (28.9) | 121 (25.8) | 6 (1.6) | 7 (2,6) |
>150,000 | 169 (30.6) | 228 (48.6) | 356 (97.8) | 258 (97,4) |
Leucocytosis | ||||
White blood cells ≤4,500 per mm3 | 218 (39.4) | 242 (51.6) | 55 (15.1) | 48 (18.1) |
White blood cells >4,500 per mm3 | 335 (60.6) | 227 (48.4) | 309 (84.9) | 217 (81.9) |
Cytolysis | ||||
ALAT ≤1 N | 385 (69.6) | 287 (61.2) | 201 (55.2) | 219 (82.6) |
ALAT 1.1-2 N | 135 (24.4) | 140 (29.9) | 117 (32.1) | 44 (16.6) |
ALAT 2.1-3 N | 27 (4.9) | 24 (5.1) | 20 (5.5) | 2 (0.8) |
ALAT >3 N | 6 (1.1) | 18 (3.8) | 26 (7.1) | 0 |
Creatinine (μmol/L) | ||||
≤120 | 507 (91.7) | 431 (91.9) | 349 (95.9) | 4 (1.5) |
121-140 | 36 (6.5) | 25 (5.3) | 8 (2.2) | 253 (95.5) |
>140 | 10 (1.8) | 13 (2.8) | 7 (1.9) | 8 (3.0) |